How It Works
How Our Formulas Are Made
What goes in our tubs, and what we leave out.
- 4.93 from 5,598 reviews
- Free US shipping on subscriptions
- 30-day returns, even opened tubs
Turn an ImmuBiome tub around and read the ingredient list before the front. Ingredients run from most to least, and on most of our tubs the first lines are mushrooms, colostrum and probiotics. You won’t find molasses or added sugar in any of them.
Key points
- Most of our formulas share a gut-first base of probiotics, prebiotics and bovine colostrum.
- We use organic, full-spectrum mushrooms that include every stage of the mushroom's life cycle.
- Our colostrum is human-grade, collected within 16 hours of calving and then gently processed.
- There's no molasses or added sugar in any ImmuBiome formula, which suits easy keepers.

A gut-first starting point
Most of our formulas are for something other than the gut: joints, breathing, focus or topline. They still start with the gut. Everything a horse eats has to be digested before it can do anything else, and the gut wall is lined with immune tissue. So nearly every formula shares a base of probiotics, prebiotics and colostrum, then adds the mushrooms suited to its job. The gut health page explains why the gut gets top billing.
Every formula is veterinarian formulated and built on over a decade with mushrooms and performance horses. The reasoning behind each one is in our whitepapers.
The four main ingredients
- Mushrooms. Organic and full spectrum, meaning every stage of the mushroom’s life cycle goes in, not only the cap. See mushrooms for which species go in which tub.
- Bovine colostrum. Human-grade, collected within 16 hours of calving and gently processed. More on the colostrum page.
- Probiotics and prebiotics. 3 billion CFU in most formulas, fed by mushroom fiber. G-Tract and Immune add Saccharomyces yeast. See prebiotics and probiotics.
- Beta-glucans. Most formulas carry a 25% minimum of 1,3/1,6 beta-glucans. The beta-glucans page has the details.
Formula Finder
Not sure which formula fits?
Answer a few quick questions in the Formula Finder and we’ll suggest a starting point, or compare formulas side by side.

What we leave out
No molasses and no added sugar. Most horses already get plenty from their regular feed, so we leave them out. That matters to owners of easy keepers and horses on low-sugar diets. If you manage a horse with metabolic concerns, bring the ingredient list to your vet, or call us at 1-888-31-HORSE for full details.
How the formulas line up
Most of the line shares that gut base, and each formula adds its own support on top:
- Immune and G-Tract for natural defenses and the digestive tract
- Breathe for healthy airways
- Joint & Recovery for joints, stifles, tendons and ligaments
- Spine & Nerve, built around Lion’s Mane, for back comfort and healthy nerve function
- Focus for keeping his mind on the job, Energy for stamina, and Lean Muscle and Strength & Stamina for topline and condition
- Super Concentrate for show and competition days alongside Focus, and Nerve Boost for extra Lion’s Mane alongside Spine & Nerve
Each one mixes into damp feed, and none of them replaces good care or your vet.
For gut-first formulas, start with our Hindgut & Ulcer Support collection.
Related pages
Questions about how we make our formulas
What does human-grade mean for a horse supplement?
It means the ingredients meet the quality standards set for human food, not the lower bar for animal feed. We source to that standard because we’d want the same for our own horses.
Why use the whole mushroom instead of just an extract?
Different parts of the mushroom carry different compounds. Full-spectrum preparations keep that variety, and some formulas add concentrated extracts where more of one part makes sense. Super Concentrate, for example, uses extracts of three Reishi species.
Are ImmuBiome formulas sweetened?
No. There’s no molasses or added sugar in any of them. Most horses take them well mixed into damp feed.
Can I feed more than one ImmuBiome formula at once?
Yes, many owners do, for example G-Tract with Lean Muscle. If you’re combining several, give us a call or check with your vet so the plan makes sense as a whole.
Where can I read ImmuBiome reviews?
Our reviews page pulls together thousands of owner reviews across every formula, and each product page shows the reviews for that formula.
Shop formulas
Shop the formulas
Every formula ships free on subscription, and you can return any tub within 30 days, even opened.
Immune
4.94 (530)
From $69
Turkey Tail, Lion’s Mane, colostrum, probiotics and at least 25% beta-glucans.
Spine & Nerve
4.9 (1276)
From $69
Lion’s Mane plus five more mushrooms for daily spine and nerve support.
More ImmuBiome formulas
Breathe
4.91 (545)
From $69
Cordyceps, Reishi and Chaga for healthy airways in dust and pollen season.
Strength & Stamina
4.96 (359)
From $69
Cordyceps, King Trumpet and colostrum for hooves, coat and stamina.
Keep reading
This page is for general information and isn’t a substitute for advice from your veterinarian. These statements have not been evaluated by the FDA. Our products are not intended to diagnose, treat, cure or prevent any disease.












