Immune Support for Horses

Looking for immune support for your horse? We start with ImmuBiome Immune—daily nutritional support for natural defenses and gut-driven immune balance through seasonal changes, travel, shows, and barn stress. Breathe is a good add-on when respiratory comfort is part of the picture.

These supplements are for nutritional support only. They are not intended to diagnose, treat, cure, or prevent disease. Work with your veterinarian for clinical care.

EQUINE IMMUNE · GUT HEALTH · SEASONAL SUPPORT

Seasonal shifts, haul days, and show schedules can all tax a horse’s natural defenses. We start with ImmuBiome Immune—Turkey Tail, Lion’s Mane, colostrum, and gut-driven immune nutrition for everyday resilience. Breathe is listed when respiratory comfort is also on your list. Use either alongside good barn management and veterinary care.

ImmuBiome Immune

ImmuBiome Immune

From $69.00
ImmuBiome Breathe

ImmuBiome Breathe

From $69.00

Helping your horse stay strong through every season

For shipping days, show season, and the changes that wear on a horse’s natural defenses
Natural defenses — blanketed horses grazing in a frosty field

Natural defenses

Daily nutritional support for your horse’s natural immune defenses through weather swings, seasonal changes, and busy routines.

Travel and show stress — chestnut horse looking out of a trailer window

Travel & show stress

Help your horse stay resilient when trailering, shows, new barns, or herd changes add stress to the routine.

Gut–immune connection — Turkey Tail and Lion’s Mane mushrooms with oats and hay

Gut–immune connection

Much of your horse’s immune activity starts in the gut. Turkey Tail & Lion’s Mane prebiotics, probiotics, colostrum, and beta-glucans support both.

Why ImmuBiome Immune for horse immune support

Our go-to for everyday immune support

We start with ImmuBiome Immune because it pairs immune-focused mushrooms with gut support—organic Turkey Tail & Lion’s Mane, 3 billion CFU of probiotics and 8,000 mg of prebiotics per serving, bovine colostrum, and fungi-derived beta-glucans (25%).

Want added respiratory focus? Breathe is a good second option, with Cordyceps, Reishi, Chaga, and colostrum for airway and respiratory wellness alongside immune care.

Use either as part of consistent feeding and your veterinarian’s wellness plan. For diagnosis, treatment, or medication decisions, always partner with your veterinarian.

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Why horse owners choose ImmuBiome

Trusted by riders every day

Owner-trusted

Immune averages 4.94★ across 500+ owner reviews

Equine-focused

Formulas designed around the horse microbiome

Ships from Idaho

UPS from Eden · free shipping on US subscriptions

30-day returns

Hassle-free returns if it is not the right fit

Horse immune support FAQ

Clear answers for horse owners
Is ImmuBiome Immune a treatment for illness or infection?
Who is this a good fit for?
Why does gut health matter for immune support?
Where can I find sizes, feeding directions, and ingredients?
Can I use Immune with other ImmuBiome formulas?
When should I choose Breathe instead?
How do I get started?

ImmuBiome Immune reviews from horse owners

Real feedback on everyday immune support
HorseProductHorsesAllergiesImmuneProductsResultsSkinCoatStuff
  • 5 stars: 494 (94%)
  • 4 stars: 32 (6%)
  • 3 stars: 1 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
A
Anonymous (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 1 to 3
2 year old immune system!

It seems to be helping my 2 year old stay healthy!

M
Marcie S. (United States)
What is your horses estimated workload?: Medium
What is your horses discipline?: Dressage
What is your horses age?: 13 to 20
Immune helps with Rain rot

My Thoroughbred is prone to bad cases of rainrot. Immune has helped reduce how often she gets it and how severe it is when she does. I recommend this product.

M
Molly O. (United States)
What is your horses estimated workload?: Heavy
What is your horses discipline?: Hunter Jumper
What is your horses age?: 8 to 12
Post surgery and recovery

We’ve been using Immune since our vet recommended it. Our horse had 3 surgeries in a year and we worry about her low WBC count after over a year of antibiotics. So glad to find this clean product with pre/postbiotics and colostrum.

B
Becky T. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 4 to 7
BEST Probiotic for my Itchy Dog!

The Immune by ImmuBiome is so effective, that I wrote a blog post about it! 5 Stars from this formerly itchy-dog owner!
https://powertoolswiththread.com/2026/06/02/a-horse-probiotic-to-ease-itchy-dogs/

N
Nancy R. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 21+

Top Page is a 27 year old Reg. Appaloosa. In 2005 I rescued him from a Premarin Ranch in Alberta Canada. He's a sweet boy! Heart of Gold. Top Page was diagnosed with Internal Pigeon Fever in Oct 2025. He was very sick and lost a lot of weight. He was on antibiotics and pain meds for over 5 months. Since learing about Immubiome in early April, it was perfect timming! Top Page was starting to get better and the Immune Formula really gave Top Page exactly what he needed! Right away I could see that he had more energy and was feeling good! He's gained weight back, he's happy and alert and I can't thank you enough for this product! I've included before and after pictures. Thank you so much! Nancy Repetski

B
Beth L. (United States)
What is your horses estimated workload?: Heavy
What is your horses discipline?: Dressage
What is your horses age?: 13 to 20
Speedy summer sore recovery

My horse's recovery from a summer sore picked up dramatically after two weeks on the loading dose of immubiome Immune.

K
Kim (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 13 to 20
Immune helped with Thrush

The last three springs I’ve battled thrush. Last year he got Lyme’s so it was especially bad this spring. I was keeping it contained with another powder, but not healing it. After 6 weeks on Immune his hooves have healed completely!
He also has heaves and allergies so I’ve added Breathe to my subscription and am hoping for more great improvements!

C
Carley (United States)
What is your horses estimated workload?: Medium
What is your horses discipline?: Western
What is your horses age?: 4 to 7
Great stuff

My mule gets at least one sarcoid a year, and so far we've been keeping them at bay with Immubiome Immune!

K
Kirsty B. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Western
What is your horses age?: 13 to 20
Love it!

ImmuBiome Immune has been wonderful for my 19 yr old QH mare who is allergic to everything! I will keep her on it for the rest of her life

J
Jacquelyn A.T. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Western
What is your horses age?: 4 to 7
Amazing Product!

I have 2 horses that both have terrible Spring / Summer allergies. We have done everything from allergies medications daily to dexamethasone when it was really bad, we thought maybe one of them is immune compromised, so I did a ton of research and found this product! Since putting both horses on it I have seen some amazing results in both horses, with no more welts or itching! I am maintaining both horses on it through winter in hopes that come spring the allergies remain at bay!

T
Tamara K. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 21+
Great for older horses

Works great on my older horse. has built up his immunity and helps his wounds to heal faster.

K
Kristine M. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 21+
Immunity Issues with Retired Mare

My mare suffered a lot from hives and being super itchy all of the time. Since we have started treating her from the inside out and helping her body not just on the surface, she’s been doing so much better. She’s also beginning to build her weight back up.

D
Darcy S.J. (United States)
What is your horses estimated workload?: Medium
What is your horses discipline?: Western
What is your horses age?: 4 to 7
Something special about this product

Do you know when your gut tells you something? Immune Bio is this product!!
My horse has skin issues and I believe this calms it down.

M
Montana (United States)
What is your horses estimated workload?: Medium
What is your horses discipline?: Western
What is your horses age?: 4 to 7
Great product!

Started the ImmuBiome Immune 2 weeks ago. Coat looks healthier and is very soft! Pleased so far with the results. Going to start using it for my 33+ year old!

T
T L. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 1 to 3
My Horse Loves It!

I bought a well bred AQHA yearling colt and when I got his genetics testing results I was dismayed to find that he is a carrier of MYHM. I want to do all I can to support his nutritional needs and immune system, so he gets a scoop of ImmuBiome Immune daily!

M
Maria E. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Western
What is your horses age?: 13 to 20
Excellent Product

We started our 16 year old Quarter Horse gelding, Manolito, on ImmuBiome Immune a year ago to help him fight habronemosis (summer sores) on the corner of his mouth. His sores healed well, and although its common for the sores to re-appear in the same place, he has been free of new sores. Thanks ImmuBiome!

P
Peggy L. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 1 to 3
Loving this

Ex Amish baby was very sick , many immune related issues , we love this product

G
Gwen B. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Western
What is your horses age?: 21+
All my horses take Immune!

From my 34 yr old paint to my 4 yr old paint my horses take Immune once daily. I bet you would never guess who is the oldest in this picture. :-)

D
Darlene (Canada)
What is your horses estimated workload?: Medium
What is your horses discipline?: Show Jumper
What is your horses age?: 4 to 7
Helped eliminate scratches

Excellent product. Gave my horses immune system the boost it needed to get rid of his scratches and his coat is finally shiny

J
Jenessa

Can this treat a mare that has a uti

See all Immune reviews

Ready for everyday immune support?

Start with ImmuBiome Immune for focused immune support—or compare Breathe for added respiratory care.

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Everyday immune support

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