Our almost 12 y.o. gelding suffers from chronic Lyme and a recent blood test showed EPM at a very low level. He used to be a daily rider for my daughter but became spooky and defiant in the ring and at jumps, as well as cranky and slightly aggressive in the stall. He's had multiple antibiotic treatments for the Lyme, but his overall condition and disposition continued to decline. We started the Spine & Nerve product less than a month ago, and are already seeing good results. His overall mood has improved and he behaves well in the stall. We haven't tried riding him again, but even bringing him to the crossties (which used to be a harrowing experience) is no longer an issue. Looking forward to continued positive results!