ImmuBiome Spine & Nerve
ImmuBiome Spine & Nerve
ImmuBiome Spine & Nerve
ImmuBiome Spine & Nerve
ImmuBiome Spine & Nerve
ImmuBiome Spine & Nerve
ImmuBiome Spine & Nerve
ImmuBiome Spine & Nerve
ImmuBiome Spine & Nerve
ImmuBiome Spine & Nerve

ImmuBiome Spine & Nerve

$69.00
Delivery

Add a name and we’ll label this item with it in your cart and on your order. Handy if you feed more than one horse.

Size: 300g

300g
600g
1.8kg
10kg

30-day returns, even opened tubs  Ships from Idaho in 1–3 business days  FEI-friendly / show-safe  Made in USA

Everyday spine & nerve support with ImmuBiome Spine & Nerve ImmuBiome Spine & Nerve is our most-reviewed formula, built around Lion’s Mane mushroom for daily nutritional support of...

Description

Everyday spine & nerve support with ImmuBiome Spine & Nerve

ImmuBiome Spine & Nerve is our most-reviewed formula, built around Lion’s Mane mushroom for daily nutritional support of spine and nerve health. It’s a favorite for the senior in the pasture and the athlete in regular work alike.

What’s inside

  • Lion’s Mane (Hericium erinaceus): The core of the formula, chosen to support healthy nerve function.
  • Five more functional mushrooms: King Trumpet, Reishi, Antrodia camphorata, and two Cordyceps species for antioxidant and immune support.
  • Bovine colostrum: Nutrients that support cellular health and resilience.
  • Probiotics & prebiotics: 3 billion CFU of probiotics and 8,000 mg of prebiotics per serving for everyday gut health and nutrient absorption.

Why horse owners choose it

  • Spine & nerve support: Formulated specifically for daily spine and nervous system support.
  • Loved by owners: Backed by more than 1,200 owner reviews and recommended by equine veterinarians.
  • Whole-horse synergy: Polysaccharides, antioxidants, colostrum, and probiotics work together.

Key benefits*

  • Supports healthy nerve function.
  • Supports a comfortable back and steady, coordinated movement.
  • Supports overall well-being and performance.

Ingredients you can trust
Lion’s Mane, King Trumpet, Reishi, Antrodia, two Cordyceps species, bovine colostrum, and a robust probiotic profile.

How to use
Mix into damp feed daily, following the label directions. Your veterinarian can help you tailor the amount to your horse’s workload and needs. If your horse shows any change in gait, coordination, or comfort, call your veterinarian first—Spine & Nerve does not replace veterinary care.

Support a comfortable back and steady nerves
Pair Spine & Nerve with good saddle fit, regular bodywork, and your veterinarian’s wellness plan for an easy daily way to support comfort and movement.

*These statements are about nutritional support. ImmuBiome supplements are not intended to diagnose, treat, cure, or prevent any disease. Talk with your veterinarian about your horse’s specific needs.

Ingredients

Per 10 g serving (label amounts where published):

Active / supportAmount
Prebiotics8,000 mg
Probiotics3 billion CFU
Core mushroomLion’s Mane (Hericium erinaceus)
Also includesKing Trumpet, Reishi, Antrodia, Cordyceps spp., bovine colostrum
Full ingredient list

Ingredients
Contains a proprietary blend of organic mushroom mycelium, primordia, fruiting bodies and extracellular compounds: Hericium erinaceus (Lion’s Mane), Pleurotus eryngi (King Trumpet), Antrodia camphorata, Ganoderma lucidum (Reishi), Cordyceps sinensis and Cordyceps militaris, bovine colostrum, fungi derived polysaccharides, Fenugreek, Bifidobacterium bifidum, Bifidobacterium longum, Enterococcus faecium, Enterococcus thermophilus, Lactobacillus acidophilus, Lactobacillus bulgaricus, Lactobacillus casei, Lactobacillus plantarum.

Active Ingredients
Per 10 Gram Serving
Probiotics: 3 billion cfu
Prebiotics: 8,000 mg
1,3-1,6 Beta Glucan: 25% min.
Colostrum: 1,500 mg

Amounts are nutritional facts from the product label / published copy. Not a drug claim.

How to Use

Based on a 1,000 lb. Horse

  • Basic Maintenance 10 g with the evening feed (one serving)
  • Higher-demand periods (per your vet) 10 g morning and 10 g evening

Directions for Use: Mix thoroughly into damp feed. One serving = 10 g

Your veterinarian can help tailor the amount to your horse’s workload.

Benefits
  • Supports spinal comfort and healthy nerve pathways*
  • Supports healthy circulation to nerve tissue*
  • Supports joint mobility*
  • Supports healthy tendons, ligaments, and bone density*
  • Supports normal comfort after work*
  • Contains the antioxidant L-ergothioneine*
  • Supports recovery after intensive training*
  • Supports a balanced immune system and gut microbiome*
  • Supports overall nerve function and health*
  • Supports mental clarity and focus*
  • Supports muscle coordination and control*
  • Supports long-term spinal comfort and stability*

*These statements are about nutritional support. ImmuBiome supplements are not intended to diagnose, treat, cure, or prevent any disease. Talk with your veterinarian about your horse’s specific needs.

Best For
  • Everyday spine & nerve support
  • Back and topline comfort
  • Steady, coordinated movement
  • Seniors and horses in regular work
  • Hoof & coat condition
  • Overall wellness
Which formula?

Choosing between formulas? The Formula Finder asks about your horse’s main goal, discipline and age, then suggests where to start.

Take the Formula Finder

Pairs well with

Spine & Nerve300g · $69.00
Nerve Boost300g · $69.00

Nerve Boost is the companion to Spine & Nerve, adding extra Lion’s Mane for horses who need more nerve support.

Both, 300g + 300g: $138.00

The Power of ImmuBiome

Immubiome blends medicinal and nutritional superfoods, known for their health benefits, using only human-grade, natural ingredients. Our unique technology combines Eastern and Western approaches to create high-quality nutraceuticals that support intestinal health, essential for top-performing equine athletes.

Day 1 Colostrum

Pure human-grade bovine colostrum, collected within 16 hours of calving and gently processed, supports immune function, normal tissue maintenance, a healthy gut lining, nutrient absorption, lean muscle, and athletic performance.

Pre & Probiotics

The equine gastrointestinal tract requires a balance of good and bad bacteria for health; ImmuBiome products support this with several probiotics at 3 billion per serving and prebiotic polysaccharides to maintain a healthy gut microbiome.

Proprietary Mushroom Blend

Our proprietary blend of organic mushroom mycelium, primordial fruiting bodies, and extracellular compounds harnesses powerful natural extracts to enhance immune function, support cellular health, and promote overall vitality.

1,3-1,6 Beta Glucan

Beta-glucans interact with immune cells to support the body's natural defenses, healthy gut function, and overall resilience.

ImmuBiome Technology

Our proprietary nutraceuticals are formulated with key ingredients designed to support the health and performance of equine athletes, including:

Full-spectrum medicinal mushrooms

100% human-grade bovine colostrum

Prebiotics and probiotics

Beta-glucan and related polysaccharides

Discover how each of these powerful ingredients contributes to the overall wellness and vitality of your horse.

Full-spectrum medicinal mushrooms

For centuries, traditional Eastern practices have used mushrooms to support health and vitality. These functional mushrooms are complex organisms that offer a range of beneficial compounds. They contain natural digestive enzymes, dietary fibers, and prebiotics, along with highly bioavailable vitamins such as vitamin D2. Additionally, they provide chelated minerals that promote natural absorption, essential amino acids, and beta-glucans. Mushrooms are also rich in polyphenols and antioxidants, including L-ergothioneine, one of the most potent antioxidants available. This combination of nutrients makes functional mushrooms a great ally in supporting overall health.

100% human-grade bovine colostrum

Our nutraceuticals feature 100% pure, human-grade bovine colostrum, collected within the first 16 hours of calving and gently processed to preserve its fragile proteins. Colostrum is rich in immune and specialized proteins that support normal immune function, tissue maintenance, and a healthy gut lining. It also supports digestion, nutrient absorption, and lean muscle growth. With nutrients that support strength, stamina, and recovery, colostrum is a valuable addition for equine athletes in intense work.

Prebiotics and probiotics

The equine gastrointestinal tract hosts a complex balance of beneficial and harmful bacteria. Maintaining this balance is crucial for your horse's overall health. Beneficial bacteria, or probiotics, help control harmful bacteria by competing for space along the intestinal wall. Prebiotics, often called "food" for probiotics, are equally important for optimal gut function. ImmuBiome products feature multiple probiotic species, delivering 3 billion per serving, along with full-spectrum mushroom preparations that act as natural prebiotics for hind-gut bacteria. Regular replenishment of prebiotics and probiotics supports a healthy and balanced gut microbiome.

Beta-glucan and related polysaccharides

β-glucan is a polysaccharide recognized for its immune health benefits and can be found in sources like mushrooms, yeast, algae, cereal grains, and bacteria. However, not all beta-glucans are equally effective in triggering immune responses. Their biological activity depends on factors such as molecular structure, branching, solubility, molecular weight, solution conformation, and methods of extraction and purification. Beta-glucan extracts are preferred because they can pass through the intestinal epithelial barrier via specialized M cells, allowing interaction with immune cells. In our nutraceuticals, we use two types of beta-glucans: mushroom and yeast-derived.

As experienced horsemen, we believe you should get what you paid for.

At ImmuBiome, we crafted these products to ensure that every serving is packed with active ingredients, free from sugars and fillers. We maintained the highest quality standards without compromise.

MOST COMPANIES

The Miraculous Mushrooms of ImmuBiome

Mycotherapy, rooted in Traditional Chinese Medicine, is now gaining popularity in the West. ImmuBiome, with over a decade of experience, crafts targeted equine supplements by carefully selecting and extracting the most beneficial compounds from medicinal mushrooms to support high-performance horses.

Each formula is unique, featuring one or more of our incredible mushrooms!

Lion's Mane

Traditionally valued for nerve and cognitive support, Lion’s Mane supports healthy nerve function and the normal maintenance of nerve tissue.

Reishi

Supports central nervous system health, muscle relaxation, and everyday comfort. Rich in antioxidants, it supports a balanced response to seasonal triggers. Functions as an adaptogen, helping the body adapt to stress (physical, mental, and environmental).

Cordyceps

Popular in Tibet, this mushroom supports mitochondrial function, cellular energy, and healthy circulation and oxygenation. It also supports normal reproductive health in breeding stallions.

Turkey Tail

Rich in polypeptides, it helps support a balanced immune system and upper respiratory health, and provides antioxidant support.

Antrodia camphorata

The most popular mushroom in Taiwan, it supports healthy liver and kidney function and the liver’s natural detox processes.

Maitake

Supports healthy immune function and helps maintain blood sugar levels already within the normal range, offering comprehensive support for overall well-being.

King Trumpet

Supports bone and skeletal health with high levels of natural L-ergothioneine, an antioxidant that supports normal comfort.

Chaga

Known as the "King of Mushrooms," it supports overall well-being, a normal stress response, and healthy aging. Rich in antioxidants like melanin, polyphenols, superoxide dismutase, and catalase, it helps neutralize free radicals.

Hear from our Veterinarians

Watch our video to hear what veterinarians are saying about ImmuBiome. For years, we've partnered with top vets to develop unique, high-quality active ingredients tailored for elite equine athletes. Our specialized nutrition is designed to meet the rigorous demands of competitive show schedules safely and effectively. ImmuBiome products are more than just supplements—they're precision-crafted tools trusted by veterinarians to deliver exceptional performance without the worry of toxic side effects or ingredient overlap. Discover the pinnacle of nature-inspired innovation in equine health.

Frequently Asked Questions

View answers to our frequently asked questions
Are ImmuBiome products show safe?
Does ImmuBiome use fillers?
Why does ImmuBiome use human-grade ingredients?
Why does ImmuBiome use colostrum vs whey protein?
Which ImmuBiome product is best for an easy keeper or metabolic horse?
Can ImmuBiome products be used with other supplements?
Do you have any tips for picky eaters?
What is GMP/cGMP?

At ImmuBiome, we are committed to ensuring your animals remain healthy, perform optimally, and recover swiftly. Your satisfaction with the results in your horse is our priority, which is why we offer a 100% Client Satisfaction Guarantee.

Real Clients. Real Results. Real Reviews.

HorseProductNerveEpmSpineSupplementImmubiomeProductsStuffLedoux
  • 5 stars: 1166 (92%)
  • 4 stars: 89 (7%)
  • 3 stars: 13 (1%)
  • 2 stars: 2 (0%)
  • 1 star: 0 (0%)
K
Kelly E. (United States)
What is your horses estimated workload?: Medium
What is your horses discipline?: Dressage
What is your horses age?: 13 to 20
Horse seems to be moving well, likes the

Horse seems to be moving well, likes the supplement.

A
Alison K. (United States)
What is your horses estimated workload?: Heavy
What is your horses discipline?: Hunter Jumper
What is your horses age?: 8 to 12
Great Product!

My young hunter had 2 foraminotomy surgeries in the last 12 months and has been on the Spine & Nerve product to help his recovery. He is doing great on it! He's back to 100% and showing again. I truly believe it helped speed up his healing. I highly recommend this supplement for neuro issues.

m
molly g. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 21+
I definitely see a difference in my horses

I definitely see a difference in my horses comfort level- he is usually a picky eater but has eaten this no problem, I do wet the feed down

S
Suzanne G.
What is your horses estimated workload?: Medium
What is your horses discipline?: Dressage
What is your horses age?: 8 to 12
Spine & Nerve works!

Spine & Nerve has really made a difference for my horse coming back from EPM. His nervous system is more even keeled, his proprioception has improved, and overall I am so pleased we finally tried this product!

A
Anonymous (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 13 to 20
We have been using on our ex big time QH show

We have been using on our ex big time QH show horse who was ridden way to much. He is now one of our best special needs horses. He is doing well on this supplement.

D
DEB C. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 21+
Spine and Nerve for the win....again!

My senior horse came down with EPM again! He is now 27 and was worse than 5 years ago! I know that using Spine and Nerve has helped in his recovery again! He is doing great now! THANK YOU for the quality product for his recovery!

R
Rachel H. (United States)
What is your horses estimated workload?: Medium
What is your horses discipline?: Show Jumper
What is your horses age?: 4 to 7
We love our immubiome products!

We love all of our Immubiome products. Spine and Nerve helps every day to support my mare in her training and show adventures.

D
Diane &.A. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 13 to 20
This helped my horse w Lymes & Cushings

This helped my horse when he had Lymes disease, which we caught early but caused falling to the knees and bad muscle atrophy. Now he has tested positive for cushings/PPID, he has sadly lost energy after taking the cushings pills but he was super energetic and playful before and physically looks great, at 20! I body clip him and he has filled out beautifully.

A
Anonymous (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Hunter Jumper
What is your horses age?: 1 to 3
ImmunBiome gives you choices to treat your horses for their different needs.

ImmuBiome gives you choices to treat your horses for their different needs. I use Spine & Nerve for epm, Breathe for my colt who had pneumonia, Lean Muscle for my rehab project, and Immune for my mare fighting infection. It's great to have these natural products to help my horses. I fully believe in the power of mushrooms. I take them myself!

S
Sonja E. (United States)
What is your horses estimated workload?: Medium
What is your horses discipline?: Other
What is your horses age?: 13 to 20
This has been a good quality product for my horse

This has been a good quality product for my horse with polyneuritis. I also have him on the Nerve Booster.

A
Anonymous (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 1 to 3
Our two-year old gelding was diagnosed with EPM

Our two-year old gelding was diagnosed with EPM. I didn't want to just rely on his prescription. I happened across your product. The quality ingredients appealed to me. He unfortunately didn't have his weekly prescription available for two weeks. I started supplementing his feed with Spine and Nerve at the recommended dosage. I noticed a tremendous difference within those two weeks. I am so impressed with your product. I see no signs of him having EPM after two months of using Spine and Nerve. I continue to supplement his feed along with our other two horses.

A
Anonymous (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 13 to 20
EPM relapses are now gone

My mare suffered from EPM, two winters in a row. She has been on Spine and Nerve and doing very well. Love this product.

R
ROSANNE B. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 21+
EPM has improved

its been 3 months now my 36 yr old has been on the spine and nerve.
She has improved but not perfect. She appears to be getting stronger every week. I plan on keeping her on this for awhile because of her age.
I know it will take time after getting the EPM

W
Wendy a.I. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Western
What is your horses age?: 21+
32 year-old quarter horse with EPM

I have a 32 year-old quarter horse that was diagnosed with EPM two years ago. He was failing and I thought it was the end of his life, but I was referred to Immubiome nerve boost products by my Equine nutritionist and he is thriving after two years.

Thank you so much, Dr Martha Faraday for your recommendation and for Immubiome for the products that are helping my horse live longer into his later years of life.

C
Cheryl W.
What is your horses estimated workload?: Medium
What is your horses discipline?: Other
What is your horses age?: 1 to 3
Love this product!! My horse recovering from EPM

Love this product!! My horse recovering from EPM has done wonders with him. Reordering to keep him on it for now.

P
Pamke526 (United States)
What is your horses estimated workload?: Medium
What is your horses discipline?: Racing
What is your horses age?: 13 to 20
We love Immubiome Spine & Nerve!

We give both of our horses Immubiome Spine & Nerve. We’ve been feeding it for about a month now and I can really tell the difference in how they move, how they look and their attitudes.
We will always use this for our two horses. ❤️❤️

T
Tina D. (United States)
What is your horses estimated workload?: Medium
What is your horses discipline?: Other
What is your horses age?: 21+
Highly recommend this supplement!!

My 21 yr old (EPM) horse, Iron, has been on this supplement for 2 months & I can tell he has improved. I highly recommend it!!

M
Michelle G. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Western
What is your horses age?: 13 to 20
Test results speak for themselves:

Huge Thank you to: Dr Shannon DeArmas @https://haymarketvet.com for first testing LeDoux and putting him on Minocycline,
& Dr Anne-marie Hancock @https://truenorthequinevet.com for all of LeDoux's Osteopath adjustments and for sending us the information for https://www.immubiome.com works amazing & for highly recommending us to the one and only amazing Michelle Werner with https://www.bigstrideshoofcare.com for fixing Lyric & Rumors , LeDoux's hoofs amazing work, she truly loves what she does and our horses truly love her shes patient lyric went through 4 different farriers until Michelle Werner she has a very kind soul she is understanding, patient thanks so much for everything you do, Lyric is active and running laps she looks very fit now helps when you have an amazing farrier . Lyric is a totally different horse with her feet she picks them up without even being tied. ❤ huge thank you to EACH AND EVERYONE OF YOU!!!
This product is what has helped LeDoux's chronic lyme disease, the numbers speak for themselves:
LeDoux's Lyme from last year! has gone from:
November 2024 his first test
OSPF: 11,668
OSPA: 1061 Equivocal
OSPC: 68 Negative
OSPF: 4332 Positive
Now: ❤
OSPA: 523 Negative
OSPC: 88 Negative
OSPF: 2238 Positive
I wish i was promoting this product and making $ but i'm not just an honest opinion ❤ We will see the results once we put Rumor on this also her numbers are high! high 9,000 Plus

M
Molly T.

I am currently treating for EPM, can I give while treating?

Vicki M.

Yes. I am finishing treatment for EPM and started my gelding Nerve and Spine as well as Nerve Boost as they were highly recommended when starting treatment. They seem to work well together.