“I definitely see a difference in my horse’s comfort level — he’s usually a picky eater but has eaten this no problem.”
Molly G.
$2.30/day
Add a name and we’ll label this item with it in your cart and on your order. Handy if you feed more than one horse.
30-day returns, even opened tubs Ships from Idaho in 1–3 business days FEI-friendly / show-safe Made in USA

Everyday spine & nerve support with ImmuBiome Spine & Nerve ImmuBiome Spine & Nerve is our most-reviewed formula, built around Lion’s Mane mushroom for daily nutritional support of...
Everyday spine & nerve support with ImmuBiome Spine & Nerve
ImmuBiome Spine & Nerve is our most-reviewed formula, built around Lion’s Mane mushroom for daily nutritional support of spine and nerve health. It’s a favorite for the senior in the pasture and the athlete in regular work alike.
What’s inside
Why horse owners choose it
Key benefits*
Ingredients you can trust
Lion’s Mane, King Trumpet, Reishi, Antrodia, two Cordyceps species, bovine colostrum, and a robust probiotic profile.
How to use
Mix into damp feed daily, following the label directions. Your veterinarian can help you tailor the amount to your horse’s workload and needs. If your horse shows any change in gait, coordination, or comfort, call your veterinarian first—Spine & Nerve does not replace veterinary care.
Support a comfortable back and steady nerves
Pair Spine & Nerve with good saddle fit, regular bodywork, and your veterinarian’s wellness plan for an easy daily way to support comfort and movement.
*These statements are about nutritional support. ImmuBiome supplements are not intended to diagnose, treat, cure, or prevent any disease. Talk with your veterinarian about your horse’s specific needs.
Per 10 g serving (label amounts where published):
| Active / support | Amount |
|---|---|
| Prebiotics | 8,000 mg |
| Probiotics | 3 billion CFU |
| Core mushroom | Lion’s Mane (Hericium erinaceus) |
| Also includes | King Trumpet, Reishi, Antrodia, Cordyceps spp., bovine colostrum |
Amounts are nutritional facts from the product label / published copy. Not a drug claim.
Based on a 1,000 lb. Horse
Directions for Use: Mix thoroughly into damp feed. One serving = 10 g
Your veterinarian can help tailor the amount to your horse’s workload.
Choosing between formulas? The Formula Finder asks about your horse’s main goal, discipline and age, then suggests where to start.
Take the Formula Finder
Spine & Nerve300g · $69.00
Nerve Boost300g · $69.00
Nerve Boost is the companion to Spine & Nerve, adding extra Lion’s Mane for horses who need more nerve support.
Both, 300g + 300g: $138.00
“I definitely see a difference in my horse’s comfort level — he’s usually a picky eater but has eaten this no problem.”
Molly G.
“Spine & Nerve helps every day to support my mare in her training and show adventures.”
Rachel H.
“We give both of our horses Immubiome Spine & Nerve. We’ve been feeding it for about a month now.”
Pam
Customer photos & quotes. Individual results vary. Nutritional support only — not intended to diagnose, treat, cure, or prevent disease.
Day 1 Colostrum
Pure human-grade bovine colostrum, collected within 16 hours of calving and gently processed, supports immune function, normal tissue maintenance, a healthy gut lining, nutrient absorption, lean muscle, and athletic performance.
Pre & Probiotics
The equine gastrointestinal tract requires a balance of good and bad bacteria for health; ImmuBiome products support this with several probiotics at 3 billion per serving and prebiotic polysaccharides to maintain a healthy gut microbiome.
Proprietary Mushroom Blend
Our proprietary blend of organic mushroom mycelium, primordial fruiting bodies, and extracellular compounds harnesses powerful natural extracts to enhance immune function, support cellular health, and promote overall vitality.
1,3-1,6 Beta Glucan
Beta-glucans interact with immune cells to support the body's natural defenses, healthy gut function, and overall resilience.
MOST COMPANIES
Watch our video to hear what veterinarians are saying about ImmuBiome. For years, we've partnered with top vets to develop unique, high-quality active ingredients tailored for elite equine athletes. Our specialized nutrition is designed to meet the rigorous demands of competitive show schedules safely and effectively. ImmuBiome products are more than just supplements—they're precision-crafted tools trusted by veterinarians to deliver exceptional performance without the worry of toxic side effects or ingredient overlap. Discover the pinnacle of nature-inspired innovation in equine health.
At ImmuBiome, we are committed to ensuring your animals remain healthy, perform optimally, and recover swiftly. Your satisfaction with the results in your horse is our priority, which is why we offer a 100% Client Satisfaction Guarantee.