Mare Hormone Balance Support for Horses

Looking for mare hormone balance support? We start with ImmuBiome Focus—daily nutritional support for everyday mood, steadiness, and mare comfort with Reishi, Chaga, magnesium proteinate, bovine colostrum, probiotics, and prebiotics.

These supplements are for nutritional support only. They are not intended to diagnose, treat, cure, or prevent any disease, and they do not replace veterinary care. If your mare has sudden behavior changes, pain signs, or reproductive concerns, talk with your veterinarian.

MARE COMFORT · EVERYDAY MOOD · CALM TEMPERAMENT

Mare owners usually want one clear starting point—not another catalog of lookalike products. This page is for mares whose everyday mood and comfort matter most: barn routines, turnout, grooming, trailering, and quiet training days. We start with ImmuBiome Focus to support everyday calm and a cooperative temperament alongside good management and your veterinarian’s guidance.

ImmuBiome Focus

ImmuBiome Focus

From $69.00

For mares with a mind of their own

Everyday support for a happier, more comfortable mare—in the barn, on the trailer, and under saddle
Everyday mare mood support — bay mare portrait in a quiet barn aisle

Everyday mare mood

Daily nutritional support for mares whose comfort and demeanor shift with barn life, turnout, and seasonal routines—focused on everyday mood and calm, not hormone treatment.

Mare barn comfort — relaxed gray mare resting on clean straw bedding

Barn & daily comfort

Help support a more settled presence through grooming, stall time, and quiet days at home—a practical everyday starting point for mare owners.

Cooperative mare temperament — attentive black mare by a wooden fence

Cooperative temperament

Reishi, Chaga, and magnesium proteinate help support calm focus and a cooperative demeanor for training, handling, and everyday work with mares.

Why Focus for mare mood & comfort

Our go-to for everyday mare calm

ImmuBiome Focus is our go-to for mare owners. It pairs organic Reishi and Chaga mushrooms with magnesium proteinate, bovine colostrum, 3 billion CFU probiotics, and 7,000 mg prebiotics to support everyday calm, mood, and cooperative temperament in mares—without claiming to regulate hormones or treat hormonal conditions.

Shopping for general calm and focus for any horse—training, travel, and shows? See our Focus & Calming hub. This page stays centered on everyday mare mood and comfort.

Use Focus alongside consistent barn routines, turnout, and your veterinarian’s wellness plan. These supplements do not replace veterinary care. If your mare has sudden behavior changes, pain signs, or reproductive concerns, talk with your veterinarian.

Shop Focus

Why horse owners choose ImmuBiome

Trusted by riders every day

Owner-trusted

Focus averages 4.95★ across 650+ owner reviews

Equine-focused

Formulas designed around the horse microbiome

Ships from Idaho

UPS from Eden · free shipping on US subscriptions

30-day returns

Hassle-free returns if it is not the right fit

Mare hormone balance support FAQ

Clear answers for horse owners
Does ImmuBiome replace veterinary care?
Who is this a good fit for?
Why start with Focus?
How is this different from the Focus & Calming hub?
Will Focus treat hormonal disorders or ovarian cysts?
Should I add another product?
How do I get started?

Focus reviews from horse owners

Real feedback on everyday calm, mood, and cooperative temperament
FocusProductHorseMareHorsesProductsStuffIngredientsResultsLife saver
  • 5 stars: 622 (95%)
  • 4 stars: 31 (5%)
  • 3 stars: 2 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
A
Anonymous (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Western
What is your horses age?: 8 to 12
Great results for anxious 8 yr. old QH

I started my 8 yr old green off-the-track QH on Focus 8 weeks ago because he was extremely watchful (watchy) and highly reactive to new sights and sounds. He also had a bad case of separation anxiety. Focus has soothed his behavior tremendously, and his training has progressed wonderfully. Thank you!

T
Theresa B. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 13 to 20
Anxiety Nixed

Our horse that has high anxiety which leads to outbreaks of hives has been much better since on this product.

D
Debra H. (United States)
What is your horses estimated workload?: Medium
What is your horses discipline?: Eventing
What is your horses age?: 8 to 12
Focus! It really helps

I have been adding Focus to my mare’s feed for a few months now and I truly believe that it is helping her stay more relaxed and focused. She will always be her “looky” and spicy self, but now I am able to redirect her and keep her attention so much better. She is a joy to ride now and not such a challenge! Thank you Immubiome!

D
Daniel B. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 4 to 7
helps a young gelding focus

he's been on this for about a year, and with a lot of good training, he has come a long way to being a big boy horse

A
Amy L.o. (United States)
What is your horses estimated workload?: Heavy
What is your horses discipline?: Hunter Jumper
What is your horses age?: 8 to 12
Show horses must have!

Absolutely love these products. All my show horses must stay on ImmuneBio. I see result my horses love the taste.

V
Vicki M. (United States)
What is your horses estimated workload?: Medium
What is your horses discipline?: Dressage
What is your horses age?: 13 to 20
Amazing Supplement

This is the first product that has actually helped with my geldings anxiety. I have tried every other calming supplement but this is the first and only one that has worked for his anxiety. Highly highly recommend it for anyone with an anxious horse!

J
Jackie (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Other
What is your horses age?: 8 to 12
Emotional Balance

Focus has been a great supplement for, what appears to be, calm on the outside, but introverted Dales Pony who is aware of everything. The worry made gut health fragile. It's a great balance of exactly what she needs and seems to be less worried about things too

A
Alexandria A. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Dressage
What is your horses age?: 1 to 3
Great product

Great product. Horse is eating it daily and it’s helping the baby brain stay focused. She’s also on lean muscle and seeing fast improvements in body scale

J
Jayne R. (United States)
What is your horses estimated workload?: Medium
What is your horses discipline?: Western
What is your horses age?: 8 to 12
Mare care

The focus seems to be working well. I hope it just continues to get better!

S
Sporti (United States)
What is your horses estimated workload?: Medium
What is your horses discipline?: Hunter Jumper
What is your horses age?: 8 to 12
Happy with this

My mare just finished a weekend-long away show. She's always an easy traveler, but she handled the travel and stabling better than ever. She has had a small setback with her hunters over fences. She was way more focused this show and handled "mistakes" with a great attitude. It all paid off in the show ring. In the top ribbons all weekend!

A
Amber E. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Western
What is your horses age?: 8 to 12
Great for Rehabs

I started my mare on the Focus supplement since she was having a hard time staying calm after she was injured. The Focus has made her much easier to handle and reduced the risk of reinjury.

R
Rosie S. (United States)
What is your horses estimated workload?: Light
What is your horses discipline?: Dressage
What is your horses age?: 4 to 7
Works great!

My mare was less anxious after starting this supplement! She is picky but she ate it no problem

M
Meagan M. (United States)
What is your horses estimated workload?: Medium
What is your horses discipline?: Hunter Jumper
What is your horses age?: 13 to 20
Love Love Love

My horse has a lot of anxiety, she tilts her head, and will pull on the reins. She has been using the FOCUS for 3 weeks and I swear she has stopped the rein pulling. She seems calmer and happier!

J
Jaime (United States)
What is your horses estimated workload?: Heavy
What is your horses discipline?: Western
What is your horses age?: 8 to 12
Best product

We have used everything under the sun, until we started using the gut and focus for our sassy mare we had not found anything that worked. 30 days later our mare is night and day this stuff is amazing ordering our second round today!!!! The natural ingredients are what sold me. She loves it and so do we 💜💜💜💜

L
Lisa S. (United States)
What is your horses estimated workload?: Medium
What is your horses discipline?: Dressage
What is your horses age?: 13 to 20
High quality, reliable results

I have had my mare on Focus for more than 5 years. I increase her dosage a small amount when she is cycling and notice an improvement in her demeanor in general. I am very happy with Focus. I especially like that there are no unnecessary ingredients in this product. Thank you.

A
Amy B. (United States)
What is your horses estimated workload?: Medium
What is your horses discipline?: Dressage
What is your horses age?: 8 to 12
ImmuBiome Focus

I am on my second order and have noticed my horse has been able to settle down quicker and focus when at new places or something going on around the barn.

K
Keri P.
What is your horses estimated workload?: Heavy
What is your horses discipline?: Hunter Jumper
What is your horses age?: 8-12
Great products with amazing results!!!

It’s been fascinating to watch my horses who have been on this product change and become much happier in their job and much more relaxed and willing!

A
Amie O.
Focus

I’ve been using the focus supplement for a little over a year now. It helps my now 6 year old Dutch Harness gelding tremendously. He used to be very tense and anxious but with the focus supplement he is able to *focus* more on me and allow me to guide him through his training. I don’t know what I would do without it!

A
Amie O.
What is your horses estimated workload?: Medium
What is your horses discipline?: Dressage
What is your horses age?: 4-7
Focus

I’ve been using the focus supplement for a little over a year now. It helps my now 6 year old Dutch Harness gelding tremendously. He used to be very tense and anxious but with the focus supplement he is able to *focus* more on me and allow me to guide him through his training. I don’t know what I would do without it!

E
Erin

Can you use multiple immubiome supplements at the same time?

M
Missy

Is Focus safe for pregnant mares

See all Focus reviews

Ready for everyday mare calm & comfort?

Start with Focus—our go-to for everyday mare calm and comfort.

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Everyday mare calm and comfort

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